Bisphosphonate treatment in osteogenesis imperfecta
نویسندگان
چکیده
منابع مشابه
Early bisphosphonate treatment in infants with severe osteogenesis imperfecta.
OBJECTIVE To evaluate prospectively the efficacy of bisphosphonate treatment in infants with severe forms of osteogenesis imperfecta (OI). STUDY DESIGN Of 10 children (6 females) with OI type III, 5 (group A) started treatment (2 mg/kg neridronate administered intravenously for 2 consecutive days, every 3 months) just after diagnosis at birth and 5 (group B) after 6 months. Ten untreated chil...
متن کاملGH in combination with bisphosphonate treatment in osteogenesis imperfecta.
OBJECTIVE To verify the effects of bisphosphonates (Bps) in combination with recombinant human GH (rGH) in pediatric osteogenesis imperfecta (OI) patients; we focused on possible improvement of bone mineral density (BMD), projected bone areas, growth velocity, and fractures risk. DESIGN A randomized controlled 1-year clinical trial on 30 prepubertal children (M:F=14:16) affected by OI (type I...
متن کاملBisphosphonate therapy for osteogenesis imperfecta. - PubMed - NCBI
Osteogenesis imperfecta is caused by a genetic defect resulting in an abnormal type I collagen bone matrix which typically results in multiple fractures with little or no trauma. Bisphosphonates are used in an attempt to increase bone mineral density and reduce these fractures in people with osteogenesis imperfecta. This is an update of a previously published Cochrane Review. To assess the effe...
متن کاملZebra lines in osteogenesis imperfecta on bisphosphonate therapy.
To cite: Sukumar SP, Balachandran K, Sahoo JP, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2012008536 DESCRIPTION A 7-year-old girl presented with a history of recurrent fractures since the age of 1 month. She was born out of a non-consanguineous marriage and had short stature with macrocephaly and triangular facies. Her sclera and teeth were normal. Sh...
متن کاملEffect of bisphosphonate treatment in osteogenesis imperfecta children in Cipto Mangunkusumo Hospital Jakarta
Results Seventy-seven OI cases (39 male), which were diagnosed at the age of 1 9 years old were recorded. Five patients underwent surgery and three patients died before commencing treatment. Nine patients received intravenous pamidronate and sixteen patients received zolendronic acid therapy. Liver and renal functions, as well as serum electrolyte levels were evaluated before and after treatmen...
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ژورنال
عنوان ژورنال: Okayama Igakkai Zasshi (Journal of Okayama Medical Association)
سال: 2012
ISSN: 0030-1558,1882-4528
DOI: 10.4044/joma.124.67